Drug intelligence / Profile preview

AlloGraf

Development stage
Preclinical
Lead developer
Escape Therapeutics
Modality
Cell Therapies
Administration
Topical
01

Overview

**AlloGraf** is an investigational, universal, permanently engrafting and immune-tolerant bilayered living human skin equivalent developed by Escape Therapeutics for partial thickness wounds. The product incorporates Escape's MorphoGel scaffold with PluraStem-derived fibroblasts and epidermal progenitors in a defined animal-free protein and/or synthetic biocompatible polymer matrix, with the aim of providing an off-the-shelf skin-replacement therapy usable across HLA types without HLA matching or adjunctive immunosuppression. ([escapetherapeutics.com](https://www.escapetherapeutics.com/allograf.html))

Other names
AlloGraf

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