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ALM0106 is a preclinical-stage small molecule endothelin A (ETA) receptor antagonist developed by Alchemedicine for the treatment of inflammatory bowel disease (IBD). The program is currently under exclusive evaluation and negotiation for licensing by Merak-Dubhe TX. As an ETA receptor antagonist, ALM0106 is designed to modulate the endothelin system, which plays a role in intestinal inflammation and tissue remodeling. The drug is intended for oral administration, aligning with Alchemedicine's focus on developing convenient small molecule therapies for chronic inflammatory conditions.
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