alnus rhombifolia pollen

Alnus rhombifolia pollen is a biologic allergenic extract derived from the white alder tree, native to western North America. It is used clinically for the diagnosis and treatment of Type I hypersensitivity reactions. As a diagnostic agent, it is applied via percutaneous or intradermal injection to elicit a wheal-and-flare reaction in sensitized individuals. In immunotherapy, gradual exposure to the extract is used to induce immunological tolerance. The extract contains proteins that act as allergens, which cross-link specific IgE antibodies bound to FceRI receptors on mast cells and basophils, triggering the release of inflammatory mediators like histamine and leukotrienes.

Other names

white alder pollenCalifornia alder pollenAlnus rhombifolia allergenic extract