Drug intelligence / Profile preview

aloe ferox leaf

Development stage
Unknown
Lead developer
Aloe Ferox
Modality
Small Molecules
Administration
Oral, Topical
01

Overview

Aloe ferox leaf refers to the dried or processed leaves of the plant Aloe ferox, a species native to South Africa. It is primarily used as a dietary supplement and in over-the-counter wellness and cosmetic products. The main bioactive compounds are anthraquinones (notably aloin), which act as stimulant laxatives by irritating the gastrointestinal tract and promoting bowel movements[2][5]. Other reported effects include potential benefits for weight loss, lipid profile improvement, mild antidiabetic activity (possibly via α-glucosidase inhibition), and skin health[2][5]. However, excessive use can lead to adverse effects such as gastrointestinal irritation or organ toxicity[2][4]. It is not an approved pharmaceutical drug but is widely marketed for its purported health benefits.

Brand names
Aloe Ferox
Other names
Cape aloebitter aloeAloe feroxAloe ferox leaf extract
02

Targets

Sucrase-Isomaltase

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