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Aloe polymannose is a polysaccharide derived from aloe, which is a key ingredient in an aloe polymannose multinutrient complex (APMC). This complex has been investigated as a dietary supplement for its potential to improve cognitive function in individuals with moderate to severe Alzheimer's dementia. The proposed mechanism of action involves the modulation of brain-derived neurotrophic factor (BDNF) levels, which are crucial for neurosynaptic function, learning, and memory. Clinical studies have shown modest improvements in cognitive outcomes and correlations between cognitive functioning and BDNF levels after supplementation with the APMC.
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