Drug intelligence / Profile preview

aloe vera

Development stage
Phase 4
Administration
Oral, Topical, Buccal, Rectal
01

Overview

**Aloe vera** is a non-standardized botanical material derived primarily from the leaves of *Aloe vera* (commonly also called *Aloe barbadensis*). Depending on the preparation, it may contain inner-leaf gel, polysaccharides such as acemannan, and other plant constituents; aloe latex is compositionally distinct and contains anthraquinone laxative compounds. Aloe vera has been studied in topical, oral, and oral-rinse preparations for radiation-related skin and oral mucosal injury, psoriasis, ulcerative colitis, xerostomia, periodontal disease, interstitial cystitis, and wound-healing applications. Clinical evidence is formulation- and indication-dependent: multiple randomized studies found no preventive benefit for radiation dermatitis, whereas limited studies have reported possible benefit in active ulcerative colitis, plaque psoriasis, and radiotherapy-induced oral mucositis. It is not a single chemically defined pharmaceutical active ingredient, and safety, pharmacology, and efficacy vary materially by plant part, extraction method, concentration, route, and product quality.

Other names
Aloe barbadensisAloe barbadensis MillerAloe vera gel新鲜芦荟液

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