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aloe vera fermentation
- Development stage
- Unknown
- Lead developer
- Ichimaru Pharcos
- Modality
- Defined Consortia → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Microbial Metabolites → Microbiome-Derived Products → Microbiome Therapeutics, Synthetic Biology Platforms → Engineered Microbial Therapeutics → Microbiome Therapeutics, Fresh FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Genetically Modified Bacteria → Engineered Microbial Therapeutics → Microbiome Therapeutics, Yeast Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Frozen FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Bacterial Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Microbial Proteins → Microbiome-Derived Products → Microbiome Therapeutics, Complex Communities → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Classical Binding Small Molecules → Small Molecules
- Administration
- Topical, Oral
01
Overview
Aloe vera fermentation is a botanical preparation produced by the fermentation of *Aloe vera* (Aloe barbadensis Miller) gel using probiotic microorganisms, such as lactic acid bacteria. This fermentation process is designed to enhance the therapeutic properties of aloe vera by increasing the bioavailability of its constituent polysaccharides, such as acemannan, and generating bioactive postbiotic metabolites. It is primarily investigated for its anti-inflammatory, analgesic, and wound-healing properties. Specifically, researchers at the Hospital of Stomatology Affiliated to Nanchang University have evaluated its efficacy as a topical treatment for recurrent oral ulceration (canker sores), where it is thought to promote mucosal repair and modulate the oral microbial community to prevent recurrence.
- Other names
- probiotic-fermented aloe verafermented aloe vera gel益生菌芦荟发酵物
02
Targets
TNFA (Tumor necrosis factor alpha (soluble))IL-6 (Interleukin 6)
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