Clinical trials
Full profile accessFollow clinical development from study design and recruitment through results.
- Trial phase
- Status
- Readouts
Drug intelligence / Profile preview
aloe vera gel + hyaluronate
- Development stage
- Preclinical
- Modality
- Implantable Devices → Device-based Delivery → Drug Delivery Systems, Transdermal Patches → Device-based Delivery → Drug Delivery Systems, Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Inhalation Devices → Device-based Delivery → Drug Delivery Systems, Classical Binding Small Molecules → Small Molecules
- Administration
- Ophthalmic
01
Overview
Aloe vera gel + hyaluronate (also known as AV/HA) is a preservative-free ophthalmic combination product used as an adjunctive treatment for glaucoma therapy-related ocular surface disease (GTOSD). It consists of aloe vera gel extract and 0.3% sodium hyaluronate. The formulation works as a lubricant by forming a protective layer over the eye's surface, while the aloe vera component provides anti-inflammatory effects by reducing pro-inflammatory cytokines and matrix metalloproteinases (MMPs). Clinical studies have indicated that these eyedrops improve signs and symptoms of GTOSD, including increasing tear break-up time and reducing ocular surface disease index (OSDI) scores.
- Brand names
- Doppelherz Eye Drops Hyaluron 0.3% + Aloe Vera
- Other names
- Aloe vera gel in 0.3% hyaluronateAloe vera/0.3% HA
02
Targets
MMP12 (Macrophage Metalloelastase)IL10 (Interleukin-10)
Beyond the preview
Go deeper on aloe vera gel + hyaluronate.
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Indications & development
Full profile accessExplore development by indication, patient population, and geography.
- Indications
- Development status
- Countries
Licensing & deals
Full profile accessTrace asset ownership, licensing agreements, and commercial partnerships.
- Partners
- Deal terms
- Milestones
Patents & exclusivity
Full profile accessExplore the patent landscape and regulatory exclusivity around an asset.
- Patents
- Expiration dates
- Exclusivity
Competitive landscape
Full profile accessCompare development programs by target, modality, and indication.
- Competing assets
- Targets
- Development stage
Research & analysis
Full profile accessConnect source evidence and development news to your research questions.
- Publications
- News
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on aloe vera gel + hyaluronate.