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Alofec

Development stage: Unknown
Lead developer: Fundación IMABIS
Modality: Stem Cell Therapies → Cell Therapies
Administration: Local Injection

Overview

Alofec is an investigational allogeneic cell therapy composed of adipose-derived mesenchymal stem cells (ASCs). Developed by the Fundación Pública Andaluza para la Investigación de Málaga en Biomedicina y Salud (FIMABIS), it is specifically designed for the treatment of faecal incontinence. The therapy involves the local, intrasphincteric injection of these stem cells, which are hypothesized to promote the regeneration of the anal sphincter muscle and modulate local inflammatory responses through paracrine signaling. This regenerative approach aims to restore sphincter function and improve quality of life for patients who have not responded to conventional treatments. Alofec has been evaluated in Phase II clinical trials in Spain.

Brand names: Alofec
Other names: Allogeneic adipose-derived mesenchymal stem cellsAllogeneic adipose-derived mesenchymal stromal cells

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