Clinical trials
Follow clinical development from study design and recruitment through results.
- Trial phase
- Status
- Readouts
Drug intelligence / Profile preview
alpha-chloralose
- Development stage
- Unknown
- Lead developer
- Wildlife Pharmaceuticals
- Modality
- Small Molecules
- Administration
- Intraperitoneal, Intravenous, Oral
01
Overview
Alpha-chloralose is a chlorinated acetal derivative of glucose that acts as a central nervous system (CNS) depressant. It is primarily used as a sedative and anesthetic in laboratory animals and wild birds, and as a rodenticide (specifically for indoor mouse control) and avicide. Chemically, it is a condensation product of chloral and glucose. Alpha-chloralose acts as a positive allosteric modulator of the gamma-aminobutyric acid type A (GABA-A) receptor complex, enhancing inhibitory synaptic transmission in the brain. This leads to progressive CNS depression, narcosis, and, in rodents at low ambient temperatures, fatal hypothermia due to impaired thermoregulation. Historically, it was also investigated as a hypnotic in human medicine, but its use has been discontinued due to adverse effects such as myoclonus and seizures.
- Brand names
- AlfamatAlphakilDorcalmRidmus AlphaSomio
- Other names
- 1,2-O-(2,2,2-trichloroethylidene)-alpha-D-glucofuranosealpha-D-glucochloraloseanhydroglucochloralaphosalchloralosechloralosanechloroalosanecloralosadulcidorglucochloralglucochloralosekrakalosmurexperglucorat
02
Targets
GABAA (Gamma-aminobutyric acid receptor)
Beyond the preview
Go deeper on alpha-chloralose.
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Indications & development
Explore development by indication, patient population, and geography.
- Indications
- Development status
- Countries
Licensing & deals
Trace asset ownership, licensing agreements, and commercial partnerships.
- Partners
- Deal terms
- Milestones
Patents & exclusivity
Explore the patent landscape and regulatory exclusivity around an asset.
- Patents
- Expiration dates
- Exclusivity
Competitive landscape
Compare development programs by target, modality, and indication.
- Competing assets
- Targets
- Development stage
Research & analysis
Connect source evidence and development news to your research questions.
- Publications
- News
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on alpha-chloralose.