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alpha lipoic acid + coenzyme Q10

Development stage: Unknown
Lead developer: UT Health San Antonio
Modality: Small Molecules
Administration: Oral

Overview

alpha lipoic acid + coenzyme Q10 is a combination of two naturally occurring mitochondrial antioxidants being investigated by The University of Texas Health Science Center at San Antonio for the treatment of vestibular function disorders in older adults. Alpha lipoic acid (ALA) serves as a cofactor for mitochondrial enzyme complexes and acts as a potent antioxidant, while coenzyme Q10 (CoQ10) is an essential component of the mitochondrial electron transport chain. The combination aims to mitigate oxidative stress and improve mitochondrial bioenergetics within the vestibular system to stabilize or improve balance and inner ear function.

Other names: ALA + CoQ10alpha-lipoic acid + ubiquinonealpha lipoic acid + coenzyme Q10

Targets

ND1 (Mitochondrial electron transport chain complex I)OADHCs (Pyruvate dehydrogenase complex and other mitochondrial alpha-keto acid dehydrogenases)AMPK (Adenosine monophosphate–activated protein kinase)

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