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Drug intelligence / Profile preview
alpha lipoic acid + folic acid + methylcobalamin + pregabalin + pyridoxine hydrochloride
- Development stage
- Unknown
- Lead developer
- SSK Pharma
- Modality
- Small Molecules
- Administration
- Oral
01
Overview
AXOFIT-PG is a fixed-dose combination capsule developed and marketed by SSK Pharma for the treatment of neuropathic pain, particularly painful diabetic neuropathy. It contains five active ingredients: pregabalin (an anticonvulsant and calcium channel modulator), methylcobalamin (an active form of vitamin B12 that aids in myelin sheath repair), alpha lipoic acid (an antioxidant that reduces oxidative stress), pyridoxine hydrochloride (vitamin B6, which supports neurotransmitter synthesis and nerve health), and folic acid (vitamin B9, which improves nerve conduction and functional recovery). Together, these components work synergistically to alleviate nerve pain, protect nerve fibers, and promote the regeneration of damaged nerve cells.
- Brand names
- AXOFIT-PG
- Other names
- alpha lipoic acid + folic acid + methylcobalamin + pregabalin + pyridoxinealpha lipoic acid + folic acid + methylcobalamin + pregabalin + pyridoxine hydrochlorideAlpha Lipoic Acid + Folic Acid + Methylcobalamin + Pregabalin + Vitamin B6AXOFIT PGmecobalamin + pregabalin + folic acid + pyridoxine + alpha lipoic acidmethylcobalamin + pregabalin + alpha lipoic acid + pyridoxine hydrochloride + folic acid
02
Targets
MTR (Methionine synthase)DHFR (Dihydrofolate reductase)DLAT (Dihydrolipoamide S-acetyltransferase)DLST (DLST (α-KGDH E2 subunit))CACNA2D1 (Voltage-gated calcium channel subunit alpha2/delta-1)α2δ (Voltage-gated calcium channel alpha-2-delta subunit)
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