alpha lipoic acid + inositol

Alpha lipoic acid + inositol is a combination dietary supplement composed of two bioactive compounds frequently used together to address metabolic and endocrine disorders. In this combination: - **Inositol** (primarily as myo-inositol or D-chiro-inositol) acts as an insulin sensitizer by functioning as a second messenger for insulin signaling pathways, thereby improving glucose metabolism and reducing insulin resistance. - **Alpha lipoic acid (ALA)** is a potent antioxidant that serves as a cofactor for mitochondrial dehydrogenase complexes. It enhances glucose uptake into cells and further improves insulin sensitivity while also reducing oxidative stress. This combination has been studied primarily for its effects on metabolic syndrome and polycystic ovary syndrome (PCOS), where it has demonstrated benefits such as improved menstrual cyclicity, ovulation rates, reduced hyperinsulinemia, better lipid profiles (increased HDL cholesterol; decreased triglycerides), lower HOMA-IR index values (a measure of insulin resistance), reduced body mass index (BMI), waist circumference reduction, and improved liver enzyme profiles. The synergistic action of these agents makes the combination particularly promising for women with PCOS—especially those who are overweight/obese or have familial diabetes—and individuals with features of metabolic syndrome[1][2][3][4][6][7].

Other names

ALA + inositolalpha-lipoic acid and inositolALA plus inositolmyo-inositol + alpha-lipoic acidD-chiro-inositol + alpha-lipoic acid