Drug intelligence / Profile preview

Alpha Plus Cream Original

Development stage
Unknown
Lead developer
Avalon Pharmaceuticals
Modality
Small Molecules
Administration
Topical
01

Overview

Alpha Plus Cream Original is a topical skin-brightening cream developed by Avalon Pharmaceuticals. It is formulated with two natural active ingredients: alpha-arbutin (1% w/w) and glabridin (0.5% w/w). Alpha-arbutin, derived from bearberry, and glabridin, extracted from licorice root, both act as potent inhibitors of tyrosinase, the rate-limiting enzyme in melanin synthesis. By blocking tyrosinase activity, the cream reduces melanin production, helping to fade dark spots, hyperpigmentation, and blemishes, and to unify skin tone. It is designed for use on the face, body, and sensitive areas such as the underarms and bikini line.

Brand names
Alpha Plus Cream Original
Other names
Alpha Plus CreamAvalon Alpha Plus CreamAvalon Pharma Alpha Plus Cream
02

Targets

TYR (Tyrosinase)

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