Drug intelligence / Profile preview

alpha-solanine

Development stage
Preclinical
Modality
Small Molecules
Administration
Oral, Intravenous, Intraperitoneal
01

Overview

**alpha-solanine** is a naturally occurring steroidal glycoalkaloid found in *Solanum* species such as potato and nightshade. It is best known as a plant toxin rather than an approved therapeutic product. In the provided publication context, alpha-solanine was evaluated **in silico** as a potential anti-Alzheimer's agent based on predicted **acetylcholinesterase inhibitory** activity and stronger docking affinity to acetylcholinesterase than rivastigmine in that computational study. However, there is no clear evidence from the provided source that alpha-solanine is an established pharmaceutical drug, clinically developed medicine, or company-sponsored development candidate for Alzheimer disease; its relevance here is primarily as a bioactive natural product and investigational research compound.

Other names
alpha-solanineα-solaninesolanine
02

Targets

SRC (Proto-oncogene tyrosine-protein kinase Src)Acetylcholinesterase

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