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alpha-synuclein vectorized antibody

Development stage: Preclinical
Lead developer: Voyager Therapeutics
Modality: Monoclonal Antibodies → Antibody-Based Therapeutics
Administration: Intravenous

Overview

**alpha-synuclein vectorized antibody** refers to an experimental **brain-penetrant anti-alpha-synuclein antibody program** rather than a single clearly identified named drug. In public disclosures, Voyager Therapeutics and AbbVie described developing vectorized antibodies directed at pathological species of alpha-synuclein for Parkinson's disease and other synucleinopathies, using blood-brain barrier shuttle technology intended to increase central nervous system exposure after systemic dosing. Because no specific molecular candidate name, sequence, or unique product identifier appears to have been publicly established for this exact term, it is best treated as a nonspecific preclinical antibody program targeting misfolded or aggregated alpha-synuclein.

Other names: alpha-synuclein vectorized antibody

Targets

SNCA (Alpha-synuclein)

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