alpha-tocopherol succinate

Alpha-tocopherol succinate is an esterified form of vitamin E (alpha-tocopherol), primarily used as a dietary supplement to treat or prevent vitamin E deficiency. It is hydrolyzed in the gastrointestinal tract to release free alpha-tocopherol for absorption. Alpha-tocopherol acts as an antioxidant and plays roles in immune function and cellular signaling. It inhibits protein kinase C activity involved in cell proliferation and differentiation and increases prostacyclin release from the endothelium to dilate blood vessels and inhibit platelet aggregation. While its main use is nutritional supplementation for deficiency states (such as fat-malabsorption disorders or abetalipoproteinemia), research has explored its potential anti-cancer properties due to effects on cell cycle regulation and apoptosis[1][3][4][6].

Brand names

White-e

Other names

alpha-tocopherol succinate.alpha.-tocopheryl succinateTOCOPHERYL ACID SUCCINATE,D-ALPHA.ALPHA.-TOCOPHEROL SUCCINATE, D-alpha-Tocopherol, succinate, D-4-Oxo-4-[[(2R)-2,5,7,8-tetramethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-3,4-dihydrochromen-6-yl]oxy]butanoic acidButanedioic acid,mono[(2R)-3,4-dihydro-2,5,7,8-tetramethyl–2–[(4R,8R)–4,8,12-trimethyltridecyl]–2H–1-benzopyran–6–yl] ester