alpha-tocopherolquinone

alpha-tocopherolquinone is an oxidized derivative of alpha-tocopherol (vitamin E). It belongs to the class of diterpenoids and is also known as vitamin E quinone. This compound has been identified in various plants and biological systems. Pharmacologically, it exhibits potent anticoagulant activity, likely through inhibition of the vitamin K-dependent gamma-glutamyl carboxylase enzyme, which prevents carboxylation of glutamyl residues in coagulation factors, thereby inhibiting platelet aggregation and blood clotting[2][4]. Additionally, it can downregulate mitochondrial respiratory activity and displays antioxidant properties after reduction to tocopherylhydroquinone[5]. Its precise mechanism of action remains incompletely elucidated.

Other names

tocopherylquinoneeutrophyl