alprostadil

TianHaiLi is a brand name for alprostadil (prostaglandin E1), a small molecule vasodilator and platelet aggregation inhibitor developed and manufactured by Shanxi Buchang Pharmaceutical. It is approved in China for the treatment of cardiac and cerebral vascular diseases, specifically chronic arterial occlusive diseases such as thromboangiitis obliterans and arteriosclerosis obliterans. The drug is typically formulated as a liposomal injection to improve stability and targeted delivery. Alprostadil works by activating prostaglandin E (EP) receptors, which increases intracellular cAMP levels, leading to smooth muscle relaxation and the inhibition of platelet activation, thereby improving microcirculation in ischemic tissues and reducing peripheral vascular resistance.

Brand names

TianHaiLi

Other names

prostaglandin E1PGE1PGE-1PGE 1alprostadilum