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alsactide
- Development stage
- Unknown
- Lead developer
- Hoechst
- Modality
- Peptides
- Administration
- Parenteral (likely Subcutaneous Or Intramuscular Injection; Specific Route Not Explicitly Stated But Inferred From Typical Use For Similar Agents)[8]
01
Overview
Alsactide is a synthetic peptide and analogue of adrenocorticotropic hormone (ACTH). It is primarily used in Italy as a diagnostic agent to assess kidney function in the context of adrenal insufficiency. Alsactide acts as a non-selective agonist of melanocortin receptors, including the ACTH receptor (melanocortin 2 receptor, MC2R), but exhibits a different profile of receptor selectivity compared to natural ACTH. Notably, it does not appear to inhibit endogenous ACTH secretion in patients with Addison's disease[8].
- Brand names
- Synchrodyn 1-17Synchrodyn1-17Synchrodyn-1-17Synchrodyn
- Other names
- alisactidealsactide
02
Targets
MC3R (Melanocortin Receptor Type 3)MC1R (Melanocortin Type 1 Receptor)MC5R (Melanocortin 5 Receptor)MC4R (Melanocortin 4 receptor)MC2R (Adrenocorticotropic Hormone Receptor)
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