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aluminium hydroxide + magnesium hydroxide (Rhône-Poulenc Rorer)
- Development stage
- Unknown
- Lead developer
- Zenith Pharmaceuticals
- Modality
- Small Molecules
- Administration
- Oral
01
Overview
ACEDONE-Z is a marketed non-systemic antacid combination containing aluminium hydroxide and magnesium hydroxide, developed and manufactured by Zenith Pharmaceuticals in Bangladesh. It is indicated for the fast, symptomatic relief of acid-related gastrointestinal disorders, including hyperacidity, peptic ulcer disease, gastritis, heartburn, sour stomach, and dyspepsia. The combination of these two antacids provides a balanced therapeutic effect: aluminium hydroxide is a slow-acting antacid with adsorbent properties that can cause constipation, while magnesium hydroxide is a faster-acting antacid with a mild laxative effect. Together, they neutralize gastric hydrochloric acid to raise stomach pH and form a protective coating over the mucosal lining without causing significant acid rebound, constipation, or diarrhea.
- Brand names
- Acedone-ZAlgexAntanilBiocidDolocidDuomealEntacydJpdroxMaaloxMagnogelMucogelOxeconePharmacidStomacid
- Other names
- aluminium hydroxide and magnesium hydroxideco-magaldroxmagnesium hydroxide + aluminium hydroxidemagnesium hydroxide and aluminium hydroxide
02
Targets
PEP (Pepsin)
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