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aluminium hydroxide + magnesium hydroxide + simethicone

Development stage: Unknown
Lead developer: nik saman darou
Modality: Small Molecules
Administration: Oral

Overview

Aluminium hydroxide + magnesium hydroxide + simethicone is an over-the-counter combination antacid and antiflatulent medication formulated as an oral suspension or chewable tablet. It is widely used for the symptomatic relief of hyperacidity, heartburn, acid indigestion, stomach upset, bloating, and gas-related discomfort. The antacid components, aluminium hydroxide and magnesium hydroxide, work by neutralizing gastric acid secreted from parietal cells of the stomach, thereby reducing acidity and relieving heartburn. Simethicone acts as an antifoaming agent by reducing the surface tension of gas bubbles in the gastrointestinal tract, causing them to coalesce into larger bubbles that can be more easily expelled, which relieves bloating and flatulence. This combination is balanced to minimize gastrointestinal side effects, as the constipating effect of aluminium hydroxide is offset by the laxative effect of magnesium hydroxide.

Brand names: AcidipanAlmaconeAltibizAluconAlumatrendAntasilBilactonCorasilDigelDigen-MPSDiovolDitopaxGasopaxGastrigelGastrogelGelosimGelusilGeri-LantaGeri-MoxLoburnaMaalox MaxMaalox PlusMintox PlusMylantaMylanta PlusNixadaNovasil PlusParactolPepsogelPepticaPolycrolPolygelProdigestSimecoSimeco PlusStomalivTriloxVeracidViscid
Other names: alumina + magnesia + simethiconealumina, magnesia, and simethiconealuminium + magnesium + simethiconealuminium hydroxide + magnesium hydroxide + simethiconealuminium hydroxide, magnesium hydroxide and simethiconealuminum + magnesium + simethiconealuminum hydroxide + magnesium hydroxide + simethiconealuminum hydroxide, magnesium hydroxide and simethicone

Targets

PEP (Pepsin)

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