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Aluminium nicotinate
- Development stage
- Unknown
- Lead developer
- Walker Laboratories
- Modality
- Small Molecules
- Administration
- Oral
01
Overview
Aluminium nicotinate is a small molecule drug that is a derivative of niacin (nicotinic acid), used primarily as a hypolipidemic agent to lower lipid levels in the blood. It consists of an aluminium salt of nicotinic acid and belongs to the class of pyridinecarboxylic acids. Its mechanism is presumed to be similar to other niacin derivatives, which act by reducing hepatic synthesis of very-low-density lipoprotein (VLDL) and low-density lipoprotein (LDL), thereby lowering cholesterol and triglyceride levels. Aluminium nicotinate has been investigated for use in cardiovascular conditions related to dyslipidemia[1][2][5][8].
- Brand names
- Micalex
- Other names
- aluminium nicotinatealuminum nicotinateniacin aluminumnicotinic acid aluminum salt
02
Targets
DGAT2 (Hepatic diacylglycerol acyltransferase 2)
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