Drug intelligence / Profile preview

aluminum chlorohydrex propylene glycol

Development stage
Unknown
Modality
Small Molecules
Administration
Topical
01

Overview

**Aluminum chlorohydrex propylene glycol** is an inorganic aluminum chlorohydrate-propylene glycol coordination complex used as a topical over-the-counter antiperspirant active ingredient. It is a distinct hydrated complex in which propylene glycol replaces some waters associated with aluminum chlorohydrate. In antiperspirant formulations, aluminum-containing species form a temporary superficial obstruction within eccrine sweat ducts, reducing the delivery of sweat to the skin surface. In the United States, it is an allowed active ingredient in OTC antiperspirant drug products at concentrations up to 25 percent, subject to the applicable monograph conditions. ([ecfr.gov](https://www.ecfr.gov/current/title-21/chapter-I/subchapter-D/part-350/subpart-B/section-350.10))

Brand names
Rehydrol II
Other names
173762-82-8ACH-7189 PG SolutionACH7189 PG SolutionACH 7189 PG Solutionaluminium chlorohydrex PGaluminium chlorohydrex propylene glycolaluminium chlorohydrex propylene glycol complexaluminium chlorohydroxide hydrate propylene glycol complexaluminium hydroxychloride hydrate propylene glycol complexaluminum chlorohydrate and propylene glycolaluminum chlorohydrex PGaluminum chlorohydrex propylene glycol complexaluminum chlorohydroxy propylene glycol complexaluminum hydroxychloride hydrate propylene glycol complexPGG6VG42HPPGG-6VG42HPPGG 6VG42HP

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