Drug intelligence / Profile preview

aluminum hydroxide + magnesium hydroxide

Development stage
Unknown
Lead developer
PAI Pharma
Modality
Implantable Devices → Device-based Delivery → Drug Delivery Systems, Small Molecules, Transdermal Patches → Device-based Delivery → Drug Delivery Systems, Inhalation Devices → Device-based Delivery → Drug Delivery Systems
Administration
Oral
01

Overview

Aluminum hydroxide + magnesium hydroxide is an over-the-counter combination antacid used to relieve symptoms of heartburn, acid indigestion, sour stomach, and upset stomach. It is also sometimes used in the management of peptic ulcer disease and gastritis. The combination works by neutralizing existing gastric hydrochloric acid through a direct chemical reaction in the stomach. Aluminum hydroxide acts as a slow-acting antacid with constipating effects; magnesium hydroxide acts more rapidly but can cause diarrhea. Their combined use balances these gastrointestinal side effects while providing effective acid neutralization[1][2][3][4][6]. This medication does not inhibit gastric acid production but rather neutralizes it after secretion.

Brand names
AlamagAlumina and MagnesiaMylanta UltimateRuloxMaalox HRFMaalox T.C.MagagelMagnaloxMaldroxalRi-Mox
Other names
aluminum-magnesium antacid suspension
02

Targets

PEP (Pepsin)

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