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Aluminum zirconium tetrachlorohydrex gly is a coordination complex used as the active antiperspirant ingredient in various over-the-counter personal care products. It works by diffusing into sweat ducts and reacting with electrolytes in the perspiration to form a physical gel-like plug. This plug temporarily blocks the eccrine sweat glands, preventing sweat from reaching the skin's surface and thereby controlling body odor and moisture. The inclusion of glycine (an amino acid) acts as a buffering agent to stabilize the complex and reduce skin irritation. While regulated as an over-the-counter drug by the FDA in the United States, it is widely considered a cosmetic ingredient globally.
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