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Aluminum zirconium trichlorohydrex gly

Development stage
Unknown
Modality
Light/Condition-Responsive Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, DNA Intercalators/Alkylators → Nucleic Acid-Directed Small Molecules → Small Molecules, Covalent Small Molecules → Small Molecules
Administration
Topical
01

Overview

Aluminum zirconium trichlorohydrex gly is a coordination complex of aluminum and zirconium chlorohydrate with glycine. It is widely used as an active ingredient in over-the-counter antiperspirant and deodorant products. The compound consists of monomeric and polymeric Zr4+ and Al3+ complexes with hydroxide, chloride, and glycine ligands. Its primary mechanism involves forming a colloidal plug within sweat pores, thereby blocking the release of sweat to the skin surface[1][2][5]. This action reduces underarm wetness (perspiration) when applied topically as a cream or stick formulation[4]. It is approved for use in personal care products such as antiperspirants.

Other names
aluminum zirconium trichlorohydrex glycinezuska

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