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ALVAC(2) melanoma multi-antigen therapeutic vaccine
- Development stage
- Unknown
- Lead developer
- Sanofi Pasteur
- Modality
- Viral Vector Vaccines → Recombinant Vaccines → Prophylactic Vaccines → Vaccines & Immunotherapeutics
- Administration
- Intradermal, Subcutaneous
01
Overview
ALVAC(2) melanoma multi-antigen therapeutic vaccine is a biological, multi-antigen therapeutic vaccine developed for the treatment of metastatic melanoma. It is based on a recombinant canarypox virus (ALVAC) vector, which is designed to deliver multiple melanoma-associated antigens, such as gp100, to the immune system. This aims to stimulate a robust immune response, specifically cytotoxic T lymphocytes (CTLs), against melanoma cells to exert a therapeutic effect.
- Other names
- ALVAC(2) multi-antigen melanoma vaccineALVAC(2)-TRICOM melanoma vaccineALVAC(2)-hB7.1/ICAM-1/LFA-3/MAGE-1,3/MART-1/gp100/NY-ESO-1
02
Targets
PMEL (Melanocyte Protein PMEL)
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