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Alyra TLR4 intrauterine product
- Development stage
- Preclinical
- Lead developer
- Alyra Biotech
- Modality
- Small Molecules
- Administration
- Intrauterine
01
Overview
Alyra TLR4 intrauterine product is a neuroimmune-modifying therapeutic being developed by Alyra Biotech (formerly referred to as Alynea) for the treatment of chronic pelvic pain and endometriosis-related symptoms. The product is designed for intrauterine administration and functions by targeting and inhibiting Toll-Like Receptor 4 (TLR4) activation within the uterus. By reducing TLR4-mediated immune system activation, the therapy aims to lessen neuroimmune-driven pelvic pain, severe dysmenorrhoea, and systemic endometriosis-related symptoms such as fatigue, mood changes, and poor sleep. This localized approach is intended to provide targeted relief while minimizing systemic side effects.
- Other names
- Alyra neuroimmune-modifying intrauterine productAlynea TLR4 intrauterine product
02
Targets
TLR4 (Toll-like receptor 4)
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