Drug intelligence / Profile preview

Alzi Stop ODF (cetirizine)

Development stage
Unknown
Lead developer
C.L. Pharm
Modality
Small Molecules
Administration
Oral
01

Overview

Alzi Stop ODF is an orally dissolving film (ODF) formulation of the second-generation antihistamine cetirizine, developed by C.L. Pharm. It functions as a potent and selective antagonist of the peripheral histamine H1 receptor. By competing with free histamine for binding sites on effector cells, it prevents the typical allergic symptoms mediated by histamine release, such as vasodilation, increased capillary permeability, and sensory nerve stimulation. This formulation is specifically designed to dissolve rapidly in the mouth without the need for water, providing a convenient delivery method for the treatment of allergic rhinitis and chronic idiopathic urticaria. The ODF technology, a specialty of C.L. Pharm, aims to improve patient compliance, particularly for individuals with difficulty swallowing tablets.

Brand names
Alzi Stop ODFAlzi-StopAlzi-Stop Film
Other names
cetirizine hydrochloride
02

Targets

HRH1 (Histamine H1 Receptor)

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