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**AM-1004** is an Arcadia Medicine preclinical neuropsychiatric drug candidate being developed for **major depressive disorder**. Arcadia describes it as a short-acting psychoactive empathogen combination therapy intended to provide an improved therapeutic profile; a company press release further characterizes it as a mildly entactogenic antidepressant designed for self-administration as a potential alternative to SSRIs and SNRIs. Its molecular structure, individual active components, and precise receptor-level pharmacology have not been publicly disclosed. ([arcadiamedicine.com](https://arcadiamedicine.com/))
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