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AMB-895 is an investigational, long-acting, oral small-molecule agonist of the glucagon-like peptide 1 receptor (GLP-1R) under development by Ambrosia Biosciences. Designed for once-weekly dosing, AMB-895 is being developed for the treatment of obesity and other metabolic or cardiometabolic disorders. By utilizing structure-based drug discovery, cryo-EM, and computational chemistry, Ambrosia aims to provide a highly differentiated oral alternative to existing injectable GLP-1 therapies with improved patient convenience and combinability.
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