Drug intelligence / Profile preview

ambrosia acanthicarpa pollen

Development stage
Unknown
Modality
Sublingual Immunotherapy → Allergy Immunotherapy → Therapeutic Vaccines → Vaccines & Immunotherapeutics, Subcutaneous Immunotherapy → Allergy Immunotherapy → Therapeutic Vaccines → Vaccines & Immunotherapeutics
Administration
Subcutaneous, Intradermal, Sublingual
01

Overview

Ambrosia acanthicarpa pollen is a biological allergen extract derived from the pollen of the Ambrosia acanthicarpa plant, also known as flatspine bur ragweed. It is used for both the diagnosis of allergies through skin testing and for treatment via allergen immunotherapy. Allergen immunotherapy involves administering gradually increasing doses of the allergen extract to desensitize the patient's immune system. This treatment aims to reduce or eliminate the symptoms of allergic conditions such as allergic rhinitis that are caused by sensitivity to this specific ragweed pollen. The extract works by modulating the immune response, shifting it from a predominantly T-helper 2 (Th2) response, which is characteristic of allergies, towards a T-helper 1 (Th1) and regulatory T-cell (Treg) response, leading to increased tolerance to the allergen. The product is a biologic and is available from multiple manufacturers, often as part of allergenic extract formulations like CENTER-AL and Western Weed Mix.

Brand names
CENTER-ALWestern Weed Mix
Other names
flatspine bur ragweed pollenannual bursage pollensand bursage pollenfalse ragweed pollenbursage ragweed pollenfranseria acanthicarpa pollen
02

Targets

IgE (Immunoglobulin E)MHC II (Major histocompatibility complex class II receptor)

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