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Ambrosia dumosa pollen is a non-standardized allergenic extract derived from the pollen of the *Ambrosia dumosa* plant, commonly known as white bursage or burro-weed. This plant is a species of ragweed native to the Mojave and Sonoran Deserts of North America. The extract is primarily utilized as a diagnostic tool in allergy testing to identify patients with hypersensitivity to ragweed pollens. It is administered via intradermal or percutaneous (scratch/prick) routes for diagnostic purposes, and may also be used in subcutaneous allergen immunotherapy to desensitize patients. As a non-standardized extract, its potency is not measured in units of biological activity relative to a standard, but it contains a complex mixture of proteins that act as allergens by cross-linking IgE on mast cells and basophils.
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