Drug intelligence / Profile preview

ambroxol + cetirizine

Development stage
Unknown
Lead developer
Caplet India
Modality
Small Molecules
Administration
Oral
01

Overview

ACT Syrup is a fixed-dose combination oral liquid formulation containing the mucolytic agent ambroxol and the second-generation antihistamine cetirizine. Developed and marketed by Caplet India, it is indicated for the symptomatic treatment of productive cough associated with allergic reactions and respiratory tract disorders. Cetirizine acts as a selective antagonist of peripheral histamine H1 receptors, effectively reducing allergy symptoms such as sneezing, runny nose, and itchy eyes. Ambroxol acts as a secretolytic and mucokinetic agent, thinning and loosening viscous mucus in the airways to facilitate expectoration and clear chest congestion. Together, the two active ingredients provide dual-action relief for patients experiencing concurrent cough and allergy symptoms.

Brand names
ACT Syrup
Other names
ambroxol hydrochloride + cetirizine hydrochloridecetirizine + ambroxol
02

Targets

GBA1 (Glucosylceramidase)HRH1 (Histamine H1 Receptor)SCN10A (Sodium channel protein type X alpha subunit)

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