Drug intelligence / Profile preview

Ambroxol hydrochloride oral solution

Development stage
Preclinical
Lead developer
Roxin Pharmaceutical
Modality
Small Molecules
Administration
Oral
01

Overview

Ambroxol hydrochloride oral solution, marketed under brand names such as Belle, is a mucolytic agent primarily used for the secretolytic therapy of bronchopulmonary diseases characterized by abnormal mucus secretion and impaired mucus transport. It functions by promoting mucus clearance, facilitating expectoration, and easing productive cough. The drug stimulates the production and release of pulmonary surfactant, increases respiratory tract secretions, and enhances ciliary activity. Additionally, it exhibits anti-inflammatory, antioxidant, and local anesthetic properties. Ambroxol hydrochloride was patented in 1966 and introduced into medical use in 1979.

Brand names
Belle
Other names
盐酸氨溴索口服溶液(贝莱)
02

Targets

GBA1 (Glucosylceramidase)NaV alpha (Voltage-gated sodium channel alpha subunit family)

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