Drug intelligence / Profile preview

amelogenin

Development stage
Phase 4
Lead developer
Libo Biotechnology
Modality
Recombinant Proteins and Enzymes
Administration
Topical
01

Overview

Amelogenin is an extracellular matrix protein essential for normal tooth development, particularly in enamel formation. It separates and supports mineral crystals as they grow during enamel development. Amelogenin self-assembles into globular aggregates and interacts with various cells involved in wound healing processes. It has been used clinically for periodontal regeneration, wound healing, and bone regeneration applications.

Brand names
Emdogain
Other names
Enamel Matrix DerivativeEMDEnamel Matrix ProteinsEMPLeucine-rich amelogenin peptideLRAPTyrosine-rich amelogenin peptideTRAPPorcine enamel matrix proteins

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