american ginseng berry extract

American ginseng berry extract (AGBE) is a botanical extract derived from the fruit of *Panax quinquefolius*. It is characterized by a high concentration of ginsenosides, which are the primary active components responsible for its biological activities. Research indicates that AGBE possesses chemopreventive properties, particularly in colorectal cancer, where it has been shown to inhibit cell proliferation and induce cell cycle arrest in the G2/M phase. When used in combination with chemotherapy agents like 5-fluorouracil (5-FU), AGBE may exhibit synergistic effects by enhancing S-phase arrest and potentially reducing the required dose and associated toxicity of the chemotherapy. Unlike the more common root extract, the berry extract contains a distinct profile of ginsenosides, such as ginsenoside Re, which contributes to its unique pharmacological profile.

Other names

Panax quinquefolius berry extract