amfecloral

**Amfecloral** is a discontinued orally administered small-molecule anorectic that was marketed in the United States as **Acutran** for obesity. It is an amphetamine-class imine prodrug formed from dextroamphetamine and chloral hydrate; following metabolism, it releases amphetamine-related stimulant activity and chloral-hydrate-related sedative-hypnotic activity. The sedative component was thought to offset the stimulant effects, and the product was characterized as having limited stimulant activity. Acutran was withdrawn from the market in 1973.

Brand names

Acutran

Other names

(±)-amphecloralalpha-methyl-N-(2,2,2-trichloroethylidene)phenethylamineamfecloralamfécloralamfecloralumamphechloralamphecloralanfecloralN-(2,2,2-trichloroethylidene)amphetamine