amino acid peritoneal dialysis solution

Amino acid peritoneal dialysis solutions are specialized intraperitoneal fluids used in patients undergoing peritoneal dialysis, particularly those with protein malnutrition. These solutions contain a mixture of essential and non-essential amino acids (such as histidine, valine, isoleucine, alanine, leucine, arginine, lysine, glycine, methionine, proline, phenylalanine, serine, threonine, tyrosine and tryptophan) formulated to compensate for protein losses during dialysis and to provide a source of nutrition when dietary intake is insufficient[4][5]. The mechanism of action involves the absorption of amino acids from the dialysate into the bloodstream through the peritoneum; this stimulates protein synthesis and inhibits protein breakdown—mimicking an anabolic response similar to food intake[1][2]. These solutions may be used alone or in combination with glucose-containing dialysates to optimize both caloric and protein delivery. They are indicated for treating or preventing malnutrition in chronic kidney disease patients on continuous ambulatory or automated peritoneal dialysis who cannot meet nutritional requirements through diet alone[4][5].

Brand names

Nutrineal PD4

Other names

amino acid-based peritoneal dialysis solutionAA-based dialysate1.1% amino acid peritoneal dialysis solution