Drug intelligence / Profile preview

amino acid supplement-UConn Health

Development stage
Unknown
Lead developer
UConn Health
Modality
Small Molecules
Administration
Oral
01

Overview

amino acid supplement-UConn Health is a specialized dietary supplement formulation developed by researchers at UConn Health for the management of nutritional deficiencies in patients with Parkinson's disease. The supplement is specifically engineered to provide essential amino acids while minimizing the competitive inhibition of levodopa (L-Dopa) transport. In Parkinson's disease, standard dietary proteins can interfere with the absorption and blood-brain barrier penetration of L-Dopa because both the drug and large neutral amino acids (LNAAs) utilize the same transport mechanism, the large neutral amino acid transporter 1 (LAT1). This targeted supplement aims to provide necessary protein-building blocks without the 'off-period' motor complications often associated with standard protein intake, thereby supporting both nutritional health and the efficacy of dopamine replacement therapy.

Other names
targeted amino acid supplementspecialized nutrition supplementamino acid supplement
02

Targets

SLC7A5 (Large neutral amino acid transporter small subunit 1)

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