Drug intelligence / Profile preview

aminophylline + fenoterol + hydrocortisone + prednisone

Development stage
Preclinical
Lead developer
Memphitis
Modality
Small Molecules
Administration
Inhalation, Intravenous, Oral
01

Overview

This is a combination medication containing four active ingredients that work together to treat respiratory conditions. Aminophylline is a bronchodilator that relaxes smooth muscles in the airways, making breathing easier. It contains theophylline which inhibits phosphodiesterase enzymes and may have anti-inflammatory effects at lower doses. Fenoterol is a beta-2 adrenergic agonist that causes bronchodilation by relaxing bronchial smooth muscle. Hydrocortisone and prednisone are corticosteroids with anti-inflammatory properties that help reduce inflammation in the airways. This combination would likely be used for the treatment of severe asthma, chronic bronchitis, emphysema, or COPD exacerbations.

02

Targets

GR (Glucocorticoid receptor)ADRB2 (β2)PDE3PDE4 (Phosphodiesterase 4A1)

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