Drug intelligence / Profile preview

aminotadalafil

Development stage
Unknown
Modality
Small Molecules
Administration
Oral
01

Overview

Aminotadalafil is a **synthetic small-molecule structural analog of tadalafil** that acts as a **phosphodiesterase type 5 inhibitor**. It is not an approved medicine and is primarily known as a **research and analytical reference compound** used in structure-activity relationship work examining how amino substitution on the tadalafil scaffold affects PDE5 binding, selectivity, and related physicochemical or metabolic properties. Aminotadalafil has also been reported as an **illicit adulterant** in products marketed for erectile dysfunction or sexual enhancement, but it has **no legitimate approved human or veterinary therapeutic use** and is sold only for research purposes.

Other names
aminotadalafil
02

Targets

PDE5A (Cyclic GMP-specific phosphodiesterase 5A)

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