ammonium chloride + sodium citrate + citric acid

Ammonium chloride + sodium citrate + citric acid is a combination pharmaceutical formulation used primarily as an expectorant to facilitate the removal of mucus from the respiratory tract. **Ammonium chloride** acts as a reflex expectorant by irritating the gastric mucosa, which in turn stimulates the vagal reflex to increase the volume of respiratory tract secretions, thereby thinning the mucus and making it easier to cough up. **Sodium citrate** and **citric acid** serve dual roles: they act as buffering agents to maintain the stability and pH of the liquid formulation, and they also possess mild mucolytic properties that help reduce the viscosity of bronchial secretions. This combination is a staple in over-the-counter (OTC) cough syrups and linctuses intended for the symptomatic relief of productive coughs associated with conditions such as the common cold, bronchitis, and other upper respiratory tract infections.

Brand names

Ammonium Chloride and Sodium Citrate Mixture BP

Other names

Ammonium Chloride and Sodium Citrate MixtureExpectorant Mixture