Drug intelligence / Profile preview

ammonium fluoride

Development stage
Unknown
Lead developer
Ivoclar
Modality
Small Molecules
Administration
Topical
01

Overview

Ammonium fluoride is an inorganic salt used primarily in dentistry for the prevention and treatment of dental caries and white spot lesions. It serves as a source of fluoride ions that promote the remineralization of tooth enamel by facilitating the formation of fluorapatite and calcium fluoride, which are more resistant to acid-mediated demineralization than the native hydroxyapatite. In addition to its clinical applications, ammonium fluoride is extensively utilized in analytical chemistry as a mobile phase additive or dopant in liquid chromatography-mass spectrometry (LC-MS) to enhance the ionization efficiency and signal intensity of various biomolecules, including lipids, fatty acids, and steroids, particularly in negative-ion mode.

Brand names
Fluor Protector S
Other names
NH4FNH-4FNH 4FNeutral ammonium fluoride

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