Drug intelligence / Profile preview

amnion chorion allograft membrane

Development stage
Phase 4
Lead developer
Merakris Therapeutics
Administration
Topical, Surgical Implant, Ophthalmic, Intraarticular, Periodontal
01

Overview

Amnion chorion allograft membrane is a biological tissue scaffold derived from the human placenta, specifically the amnion and chorion layers. It is processed to maintain the structural integrity of the extracellular matrix and contains various growth factors (e.g., PDGF, TGF-β, FGF), cytokines, and specialized proteins that promote wound healing, reduce inflammation, and minimize scar formation. It is commonly used in dental procedures for gingival recession and guided tissue regeneration, as well as in chronic wound management (e.g., diabetic foot ulcers) and ophthalmic surgeries.

Brand names
EpiFixNuShieldAmnioBandBio-DBio-RetainAmnioFill
Other names
dHACMdehydrated human amnion/chorion membranehuman amnion chorion allograftAC membrane
02

Targets

TGFBR (TGF-beta receptor)PDGFR (PDGFR family)FGFR (Fibroblast growth factor receptor)NeuraminidaseEGFR T790M (Epidermal growth factor receptor T790M mutant)

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