Drug intelligence / Profile preview

amomum tsaoko flavonoids

Development stage
Unknown
Modality
Allosteric Modulators → Classical Binding Small Molecules → Small Molecules, Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules
Administration
Oral
01

Overview

**Amomum tsaoko flavonoids** are a group of flavonoid compounds extracted from the fruit of the plant *Amomum tsaoko* Crevost et Lemarie, a traditional Chinese medicinal and food plant commonly used as a spice[1][3]. Over 300 chemical compounds have been reported from *Amomum tsaoko*, with at least 29 identified flavonoids, including (+)-epicatechin, isoquercitrin, astragalin, kaempferol-3-O-rutinoside, and procyanidin B2[1][4]. These flavonoids have been studied for their **antioxidant**, **antidiabetic (α-amylase and α-glucosidase inhibitory)**, **anti-inflammatory** (via inhibition of nitric oxide production and the TLR4/NF-κB/NLRP3 pathway), and **gut microbiota-modulating** effects[1][3][5]. In preclinical models, they have improved glucose tolerance, lowered blood glucose and insulin, reduced oxidative stress (by decreasing malondialdehyde and increasing superoxide dismutase), and protected pancreatic tissue in diabetic rats[1]. They have also shown efficacy in murine models of ulcerative colitis and constipation, modulating the gut microbiome and serotonergic signaling pathways[3][5]. No information was found on their development by a pharmaceutical company; their use remains largely investigational in functional foods and traditional medicine[1][3][4].

Other names
Amomum tsao-ko flavonoidsAT flavonoidsATFTsaoko Fructus flavonoids
02

Targets

AMY (Pancreatic alpha-amylase)NOS2 (Nitric Oxide Synthase 2)Sucrase-Isomaltase

Beyond the preview

Go deeper on amomum tsaoko flavonoids.

Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.

Clinical trials

Full profile access

Follow clinical development from study design and recruitment through results.

  • Trial phase
  • Status
  • Readouts

Indications & development

Full profile access

Explore development by indication, patient population, and geography.

  • Indications
  • Development status
  • Countries

Licensing & deals

Full profile access

Trace asset ownership, licensing agreements, and commercial partnerships.

  • Partners
  • Deal terms
  • Milestones

Patents & exclusivity

Full profile access

Explore the patent landscape and regulatory exclusivity around an asset.

  • Patents
  • Expiration dates
  • Exclusivity

Competitive landscape

Full profile access

Compare development programs by target, modality, and indication.

  • Competing assets
  • Targets
  • Development stage

Research & analysis

Full profile access

Connect source evidence and development news to your research questions.

  • Publications
  • News
  • Analysis

Bring the full picture into focus.

See how Gosset can support your research on amomum tsaoko flavonoids.

Explore the full profile

Gosset Free

Get started with Gosset.

Enter your work email and we’ll be in touch with next steps.

Work email preferred.

Book a call