amomum villosum polysaccharide

Amomum villosum polysaccharide refers to one or more polysaccharide fractions purified from the fruit of Amomum villosum Lour., a medicinal plant widely used in traditional Chinese medicine for gastrointestinal and digestive disorders[1][3]. Polysaccharides from A. villosum are large, heterogeneous carbohydrate macromolecules—primarily galactose, glucose, arabinose, and rhamnose—that may display varying molecular weights and structural features depending on extraction and purification methods[1][4]. Several fractions have been isolated (such as AVPG-1, AVPG-2, and AVLP-2), each displaying distinct molecular structures and compositions[1][4]. Amomum villosum polysaccharides have been shown to exhibit immunomodulatory, antioxidant, anti-inflammatory, and gastroprotective activities in preclinical models[4][3][6]. Notably, specific fractions (e.g., AVLP-2) demonstrate protective effects against oxidative stress and inflammation, inhibiting the excessive generation of reactive oxygen species and regulating cytokine expression in cell and animal models[4]. AVP can also interact with starch, altering gelatinization and digestion properties, potentially inhibiting starch digestibility and improving thermal stability[2]. The specific mechanisms are attributed to the ability to scavenge free radicals, modulate inflammatory signaling (including NF-κB), and influence gut immunity and microbiology[4][3][5]. These polysaccharides are not developed or regulated as pharmaceuticals but are often studied as bioactive food or herbal supplement ingredients[6][8].

Other names

AVPAVPG-1AVPG1AVPG 1AVPG-2AVPG2AVPG 2AVLP-2AVLP2AVLP 2amomum villosum lour. polysaccharide