Drug intelligence / Profile preview

Amosartan

Development stage
Phase 4
Lead developer
Hanmi Pharmaceutical
Modality
Small Molecules
Administration
Oral
01

Overview

Amosartan is a fixed-dose combination pharmaceutical drug primarily used for the treatment of hypertension (high blood pressure) and, in some formulations, hyperlipidemia (dyslipidemia). The original formulation combines two active ingredients: amlodipine camsylate (a calcium channel blocker) and losartan potassium (an angiotensin II receptor blocker). This dual mechanism helps relax blood vessels and lower blood pressure by blocking calcium influx into vascular smooth muscle cells and inhibiting the action of angiotensin II on its receptor. Extended formulations such as Amosartan Q add rosuvastatin (a statin for cholesterol reduction), while Amosartan XQ further includes ezetimibe for additional lipid-lowering effects. These combinations are designed to improve medication adherence and provide integrated management of cardiovascular risk factors[2][3][5][7].

Brand names
AmosartanAmosartan QAmosartan PlusAmosartan XQ
Other names
amlodipine + losartanamlodipine camsylate + losartan potassiumamlodipine besylate + losartan potassium
02

Targets

HMGCR (3-hydroxy-3-methylglutaryl-coenzyme A reductase)NPC1L1 (Niemann-pick C1-Like 1 transporter)CACNA1C (Voltage-dependent L-type calcium channel subunit alpha-1C)AGTR1 (Angiotensin II Type-1 receptor)

Beyond the preview

Go deeper on Amosartan.

Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.

Clinical trials

Full profile access

Follow clinical development from study design and recruitment through results.

  • Trial phase
  • Status
  • Readouts

Indications & development

Full profile access

Explore development by indication, patient population, and geography.

  • Indications
  • Development status
  • Countries

Licensing & deals

Full profile access

Trace asset ownership, licensing agreements, and commercial partnerships.

  • Partners
  • Deal terms
  • Milestones

Patents & exclusivity

Full profile access

Explore the patent landscape and regulatory exclusivity around an asset.

  • Patents
  • Expiration dates
  • Exclusivity

Competitive landscape

Full profile access

Compare development programs by target, modality, and indication.

  • Competing assets
  • Targets
  • Development stage

Research & analysis

Full profile access

Connect source evidence and development news to your research questions.

  • Publications
  • News
  • Analysis

Bring the full picture into focus.

See how Gosset can support your research on Amosartan.

Explore the full profile

Gosset Free

Get started with Gosset.

Enter your work email and we’ll be in touch with next steps.

Work email preferred.

Book a call