amoxicillin + clarithromycin + lansoprazole + metronidazole

This combination is a type of concomitant therapy used for Helicobacter pylori (H. pylori) eradication. It consists of amoxicillin (a penicillin antibiotic), clarithromycin (a macrolide antibiotic), metronidazole (an antibiotic and antiprotozoal), and lansoprazole (a proton pump inhibitor). The antibiotics work by killing bacteria or preventing their growth, while lansoprazole decreases stomach acid production, creating a less acidic environment that weakens H. pylori bacteria and allows the antibiotics to work more effectively. This four-drug regimen is particularly useful in areas with high resistance to clarithromycin or metronidazole, as the combination helps overcome resistance to individual antibiotics.

Other names

Concomitant therapy